Is COVID-19 The Main Reason for “Brain Fog”?

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  • A quarter of Covid-19 patients in a Mount Sinai Health System registry experienced some issues with their memory
  • A relatively high frequency of cognitive impairment several months after patients contracted COVID-19
  • The authors noted the possibility for bias in the sample

According to a new study Cognitive impairment, described as brain fog,  can persist for months in Covid-19 patients, even for some who were not hospitalized, reports CNN.

Brain fog

The U Centers for Disease Control and Prevention includes difficulty thinking or concentrating — sometimes referred to as “brain fog” — on its list of post-Covid conditions.

The research, published Friday in the journal JAMA Network Open, found that nearly a quarter of Covid-19 patients in a Mount Sinai Health System registry experienced some issues with their memory — and although hospitalized patients were more likely to have such brain fog after a coronavirus infection, some outpatients had cognitive impairment too.

“This pattern is consistent with early reports describing a dysexecutive syndrome after COVID-19 and has considerable implications for occupational, psychological, and functional outcomes,” the researchers wrote. Separate research, published in April in the journal Lancet Psychiatry, found that as many as 1 in 3 people with Covid-19 had longer term mental health or neurological symptoms.

About the study

The new study included data, from April 2020 through May 2021, on 740 Covid-19 patients with no history of dementia. The average age of patients was 49. Cognitive functioning was assessed for each patient and the researchers analyzed the frequency of cognitive impairment among the patients.

Outcome

“In this study, we found a relatively high frequency of cognitive impairment several months after patients contracted COVID-19. Impairments in executive functioning, processing speed, category fluency, memory encoding, and recall were predominant among hospitalized patients,” Jacqueline Becker and her colleagues at the Icahn School of Medicine at Mount Sinai in New York, wrote in the study.

Among all the patients, the researchers found that 15% showed deficits in phonemic fluency in their speaking; 16% in a set of mental skills called their executive functioning; 18% showed deficits in their cognitive processing speed; 20% in their ability to process categories or lists; 23% in memory recall and 24% in memory encoding, among other impairments.

Hospitalized patients

When it came to memory recall, the researchers found 39% of hospitalized patients had impairment in that area compared with 12% of outpatients. When it came to memory encoding, the data showed that 37% of hospitalized patients had impairment compared with 16% of outpatients.

Sampling bias

The authors noted the possibility for bias in the sample because patients came to Mount Sinai Health System because they were experiencing symptoms.

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Source: CNN